Studies on the Synthesis of Protein Analogues. XX-XXII. XXI. Polyanhydro-L-aspartic Acid (Poly-L-Succinimide)
نویسندگان
چکیده
منابع مشابه
Preparation of poly(butylene succinate) copolymers including L-aspartic acid
Copolymers of poly(butylene succinate) (PBS) with amino acids were produced from succinic acid (1), 1,4-butanediol (2) and 1 mol% of various amino acids. Their reaction time and molecular weight, as well as thermal and mechanical properties, were studied. The reaction time for polymerization was found to increase as the amount of amino acid was increased, except when L-aspartic acid (3) was use...
متن کاملMetabolism of L-aspartic acid.
Aspartic acid, like glutamic acid, occupies a central position in amino acid metabolism. In most tissues it takes part in the transamination reaction (1). In the liver and the kidney, where all amino acids undergo cleamination, the rate of this process for aspartic acid is second only to glutamic acid (2). For these reasons, one would expect the exchange of amino nitrogen of aspartic acid with ...
متن کاملOxovanadium(IV) complexes of salicyl-L-aspartic acid and salicylglycyl-L-aspartic acid.
The dipeptide and tripeptide analogues salicyl-L-aspartic acid (Sal-L-Asp) and salicylglycyl-L-aspartic acid (SalGly-L-Asp) were synthesized and their protonation and complex formation with V(IV)O2+ were studied in aqueous solution through the use of pH-potentiometry and spectroscopic (UV-Vis, CD and EPR) techniques. The phenolate terminus proved to be a good anchoring site to promote (i) the m...
متن کاملBiodegradability and tissue reaction of random copolymers of L-leucine, L-aspartic acid, and L-aspartic acid esters.
A series of copoly(alpha-amino acids) with varying percentages of hydrophilic (L-aspartic acid) and hydrophobic monomers (L-leucine, beta-methyl-L-aspartate, and beta-benzyl-L-aspartate) were implanted subcutaneously in rats and the macroscopic degradation behavior was studied. Three groups of materials (A,B,C) with different ranges of hydrophilicity were distinguished: A) hydrophobic materials...
متن کاملA route to anionic hydrophilic films of copolymers of L-leucine, L-aspartic acid and L-aspartic acid esters
A series of copolymers of L-leucine and/3-benzyI-L-aspartate [Leu/Asp(OBz)] covering the range 30-70 mol % of L-leucine, was synthesized by the N-carboxyanhydride (NCA) method. The copolymers were characterized by elemental analysis, infra-red spectroscopy and viscometry. For all compositions high molecular weight copolymers were prepared with excellent film-forming properties. Tercopolymers of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nippon kagaku zassi
سال: 1960
ISSN: 0369-5387,2185-0917
DOI: 10.1246/nikkashi1948.81.4_620